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Dr. Wan, Dr. Marx and Dr. Morrow

At the Cardiac Arrhythmia and Ion Channel Research Center of Columbia University, physician-scientists Dr. Elaine Wan and Dr. Steven Marx, work together to develop new methods of diagnosing and treating arrhythmias. Our scientists have made major advances in understanding the molecular and cellular bases for and the fundamental mechanisms of complex, life-threatening arrhythmias and sudden cardiac death.

Our research program is focused in two major areas:

(1) Cardiac: studying the regulation of ion channels in normal and pathological conditions in the heart. Altered cardiac ion channel function is associated with heart failure and arrhythmias.

(2) Vasculature: understanding molecular mechanisms leading to vascular smooth muscle proliferation, migration and contractility. 



  • July

Dr. Melki will be presenting the poster “Panoramic Optical Mapping and Micro-Computed Tomography for 3D Characterization of the Arrhythmogenic Substrate in Murine Hearts”, at the Heart Rhythm Society 2021 Annual Scientific Sessions, Boston, MA on July 30th, 2021.

The poster will be presented on Friday July 30th and she has also been selected to take part in the Cardiac Electrophysiology Society Young Investigator Award Competition, as a finalist nominee on Wednesday, July 28th, 2021.

Amar D. Desai, Brian C. Boursiquot, Catherine J. Moore, Hasan Garan, Rakesh Gopinathannair, Elaine Y. Wan, Marc P. Waase, Geoffrey A. Rubin, "Autonomic Dysfunction in COVID-19", Heart Rhythm Society 2021 Annual Scientific Sessions, Boston, MA (Poster Presentation).

  • October 

       Cardiac arrhythmias in patients with COVID-19

       Digital Health and the Care of the Arrhythmia Patient; What Every Electrophysiologist Needs to Know.  

  • September

       Feasibility of near-infrared spectroscopy as a tool for anatomical mapping of the human epicardium.

       Catheter Ablation Lesion Visualization With Intracardiac Strain Imaging in Canines and Humans.

  • April

       Restructuring Electrophysiology During the COVID-19 Pandemic: A Practical Guide From a New York City Hospital Network.

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